Easing the burden of neglected diseases

We develop medicines to ease the burden of neglected diseases on underserved communities worldwide.

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New medicines for lasting change

We’re tackling the world’s most challenging diseases so that communities can thrive around the world

FEATURED

Report: Advancing Global Health Innovation Through Europe-Africa Collaboration

A joint call from Product Development Partnerships for Sustained Funding to EDCTP under the Next Framework Programme for Research and Innovation (FP10)

what you should know

Key statistics

KEY STAT

001

1b+

Over 1 billion people suffer from neglected tropical diseases.

KEY STAT

002

2b+

Over 2 billion people struggle to access even basic medicines.

KEY STAT

003

<2%

U.S. FDA approved medicines between 2005 - 2024 were for neglected diseases.

WHO WE ARE

The not-for-profit pharmaceutical company

MDGH provides solutions to some of the world's most urgent health challenges, without having to rely on a commercial return on investment in the development of medicines.

As a not-for-profit pharmaceutical company, MDGH is on a mission to eliminate neglected diseases by developing, securing regulatory approval for, and manufacturing and supplying medicines for many of the world’s most underserved communities.

We are currently developing two medicines: moxidectin and dovramilast. Together, these medicines target seven different neglected diseases that collectively affect more than 1 billion people.

Our Pipeline

THE WORK WE DO

Our focus areas

River Blindess

River blindness (onchocerciasis) is a parasitic worm infection spread by the bite of a black fly, which lead to severe itching, disfiguring skin changes and even blindness.

Lymphatic Filariasis

Lymphatic filariasis (elephantiasis), caused by parasitic worms spread by infected mosquitoes, affects the lymph system leading to severe swelling, chronic pain and long-term disability.

Leprosy type 2 reaction

Leprosy type 2 reaction can occur as a complication of leprosy, most commonly in patients who are receiving multi drug therapy but can occur before treatment or long after treatment is completed.

Scabies

An infectious skin condition affecting more than 200 million people at any one time.

Soil-transmitted helminth infections

Among the most common of all infections with an estimated 1.5 billion people infected worldwide.

Strongyloidiasis

An infectious skin condition affecting more than 200 million people at any one time.

Tuberculosis

Primarily affecting the lungs, tuberculosis remains the leading cause of infectious death worldwide.

MDGH rolls out the first treatment for river blindness in over 30 years.

In January 2025 our team, with the support of Ghana Health Services, began distributing moxidectin in Ghana. The treatment has already reached over 120,000 people.

View our work

Celebrating 20 years of MDGH

HOW WE WORK

We have a unique approach

Developing Medicines

Our unique business model prioritises impact over profit. By focusing on medicines already in the clinical development phase, we increase the probability of success, shorten the time to impact, and minimise the potential financial loss due to failure. After development we shepherd our medicines through the relevant regulatory pathways and hold and maintain the respective authorisations to ensure access by those who need the medicines most.

Addressing the gap

Between 2005 and 2024, more spacecraft were sent to the moon than new U.S. FDA-approved medicines were developed for neglected diseases and tuberculosis. We’re addressing this innovation gap by developing improved treatments that can transform health outcomes for people in low- and middle-income communities.

Source: Ashigbie et al 2025 Nature Reviews Drug Discovery https://en.wikipedia.org/wiki/List_of_mission_to_the_Moon#2000

Working Collaboratively

We’re already making progress in addressing global health inequities, but we’re just one piece of a larger puzzle. Our work and its impact on global health is only made possible through productive partnerships with industry, research institutes, governments, impact investors and donors.

Join us

Support us through donations, partnerships, and investments to drive change and build a better future together

Support us

Donations & Philanthropic giving

Support the development of life-changing medicines for over one billion people affected by neglected diseases.

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Workplace Giving

Make regular pre-tax donations that help accelerate access to vital treatments for underserved communities.

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Impact Investing

Invest in the development of new medicines for neglected diseases, with the opportunity for financial return and measurable global impact.

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Latest News

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Informations en français

Documents sur MDGH, les maladies négligées et le développment de médicaments.

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MDGH Resources

Resources on MDGH, neglected diseases, and medicine development.

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Careers at MDGH

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